Datasets
Listed below are a variety of manually and programmatically compiled datasets related to either dexamethasone perturbation or perturbation of a known genetic target of dexamethasone.
Some datasets have accompanying Jupyter Notebooks comprised of code for benchmarking the specific dataset, which can be found on the Code page.
Dexamethasone
RNA-seq
- Compiled Spreadsheet of Dexamethasone Studies (Google Sheets)
- Computed Signatures (Webpage)
Microarray
- Drug Matrix Data - CodeLink Arrays (File Download)
- Dex and Related Drug Pertubations from CREEDS (File Download)
- Dexamethasone Gene Signatures from GEN3VA (Webpage)
L1000 Chemical Perturbation Profiles
- Dexamethasone Perturbation Profiles (File Download)
L1000 Signatures
- Dexamethasone Perturbation Signatures (File Download)
Dexamethasone Targets
RNA-seq
- Compiled Spreadsheet of Dex Target Studies (Google Sheets)
ChIP-Seq
- NR3C1 Gene Sets from ChEA and ENCODE (Google Sheets)
- NR3C1 Entries from GEO (Google Sheets)
L1000 CRISPR Knockout Profiles
- NR0B1 CRISPR Knockout Profiles (File Download)
- NR1I2 CRISPR Knockout Profiles (File Download)
L1000 shRNA Knockdown Profiles
- NR3C1 Knockdown Profiles (File Download)
- NR0B1 Knockdown Profiles (File Download)
L1000 Overexpression Profiles
- NR3C1 Overexpression Profiles (File Download)
- NR0B1 Overexpression Profiles (File Download)
- NR1I2 Overexpression Profiles (File Download)
L1000 Signatures
- NR3C1 Knockdown Signatures (File Download)
- NR3C1 Overexpression Signatures (File Download)