Omics Mining for the Illuminating the Druggable Genome Project

NEK4

Top 200 predicted GO terms

Go termZ-score
cilium movement (GO:0003341) 1.7550840544183
epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) 1.75350800295281
cilium or flagellum-dependent cell motility (GO:0001539) 1.73326821928711
neural tube formation (GO:0001841) 1.69623012428466
epithelial cilium movement (GO:0003351) 1.63478504110736
sperm motility (GO:0030317) 1.62214647173498
male meiosis I (GO:0007141) 1.61966249884268
axonemal dynein complex assembly (GO:0070286) 1.58616997173033
reciprocal DNA recombination (GO:0035825) 1.55320213229101
reciprocal meiotic recombination (GO:0007131) 1.55320213229101
sulfation (GO:0051923) 1.50506287716429
cilium organization (GO:0044782) 1.48916509231944
cilium assembly (GO:0042384) 1.47513409144945
axoneme assembly (GO:0035082) 1.42137169040436
piRNA metabolic process (GO:0034587) 1.42095817105025
L-fucose metabolic process (GO:0042354) 1.41913063481311
L-fucose catabolic process (GO:0042355) 1.41913063481311
fucose catabolic process (GO:0019317) 1.41913063481311
oxidative demethylation (GO:0070989) 1.40571486420923
DNA methylation involved in gamete generation (GO:0043046) 1.40409291793056
protein K11-linked deubiquitination (GO:0035871) 1.39489334390782
regulation of hippo signaling (GO:0035330) 1.39416198376473
centriole replication (GO:0007099) 1.38300654293009
spinal cord motor neuron differentiation (GO:0021522) 1.37811674083075
rRNA catabolic process (GO:0016075) 1.37649807509121
synapsis (GO:0007129) 1.37562180491361
meiotic cell cycle (GO:0051321) 1.36705830809941
cysteine metabolic process (GO:0006534) 1.36624604533031
motile cilium assembly (GO:0044458) 1.34639656752497
cilium morphogenesis (GO:0060271) 1.33654386966721
male meiosis (GO:0007140) 1.33338942567777
protein localization to cilium (GO:0061512) 1.33147598530474
acrosome assembly (GO:0001675) 1.33097135851303
positive regulation of response to tumor cell (GO:0002836) 1.32956426472599
regulation of immune response to tumor cell (GO:0002837) 1.32956426472599
regulation of response to tumor cell (GO:0002834) 1.32956426472599
positive regulation of immune response to tumor cell (GO:0002839) 1.32956426472599
negative regulation of DNA-dependent DNA replication (GO:2000104) 1.3262508371276
cellular component assembly involved in morphogenesis (GO:0010927) 1.31713099291245
regulation of cilium movement (GO:0003352) 1.31649184175346
determination of left/right symmetry (GO:0007368) 1.31425733899268
establishment of protein localization to Golgi (GO:0072600) 1.3098778363338
behavioral response to nicotine (GO:0035095) 1.30965040394417
nonmotile primary cilium assembly (GO:0035058) 1.30834983489725
interkinetic nuclear migration (GO:0022027) 1.3041111793018
regulation of rhodopsin mediated signaling pathway (GO:0022400) 1.30199280870953
photoreceptor cell development (GO:0042461) 1.28544827545107
ncRNA catabolic process (GO:0034661) 1.27978966297858
determination of bilateral symmetry (GO:0009855) 1.2734946147989
photoreceptor cell maintenance (GO:0045494) 1.27236837845729
protein polyglutamylation (GO:0018095) 1.26800263099944
regulation of telomere maintenance (GO:0032204) 1.26424776277673
embryonic epithelial tube formation (GO:0001838) 1.26277376800669
regulation of acrosome reaction (GO:0060046) 1.2590768493029
somatic hypermutation of immunoglobulin genes (GO:0016446) 1.25576276374522
somatic diversification of immune receptors via somatic mutation (GO:0002566) 1.25576276374522
centrosome duplication (GO:0051298) 1.25397931754002
negative regulation of transcription regulatory region DNA binding (GO:2000678) 1.24914818382105
retinal cone cell development (GO:0046549) 1.24889012582983
meiosis I (GO:0007127) 1.24887218183317
negative regulation of multicellular organism growth (GO:0040015) 1.24664165930851
regulation of nuclear cell cycle DNA replication (GO:0033262) 1.24248957952511
epithelial tube formation (GO:0072175) 1.24048217003365
specification of symmetry (GO:0009799) 1.23891694519334
negative regulation of telomere maintenance (GO:0032205) 1.23761403740091
centriole assembly (GO:0098534) 1.23368395395368
smoothened signaling pathway (GO:0007224) 1.22644450307509
proline transport (GO:0015824) 1.22544192160513
spermatid development (GO:0007286) 1.22407317783086
eye photoreceptor cell development (GO:0042462) 1.22078779309689
protein targeting to Golgi (GO:0000042) 1.21831588506242
microtubule organizing center organization (GO:0031023) 1.21715968436016
cardiovascular system development (GO:0072358) 1.21682145775495
serine family amino acid catabolic process (GO:0009071) 1.21670878979893
polyol catabolic process (GO:0046174) 1.21004410380248
left/right axis specification (GO:0070986) 1.20863361802535
centrosome organization (GO:0051297) 1.20764988684578
preassembly of GPI anchor in ER membrane (GO:0016254) 1.20557721284366
cell projection assembly (GO:0030031) 1.20465926359192
methionine biosynthetic process (GO:0009086) 1.20374408264932
thyroid hormone metabolic process (GO:0042403) 1.20330234377481
replication fork processing (GO:0031297) 1.2008950830759
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:2000060) 1.1995198027187
regulation of translation, ncRNA-mediated (GO:0045974) 1.19446453251448
negative regulation of translation involved in gene silencing by miRNA (GO:0035278) 1.19446453251448
negative regulation of translation, ncRNA-mediated (GO:0040033) 1.19446453251448
DNA damage induced protein phosphorylation (GO:0006975) 1.1916246503202
regulation of microtubule-based movement (GO:0060632) 1.18942116156822
cellular ketone body metabolic process (GO:0046950) 1.18858576310319
fucosylation (GO:0036065) 1.18800960319608
rhodopsin mediated signaling pathway (GO:0016056) 1.18650124289247
magnesium ion transport (GO:0015693) 1.1848060328773
phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) 1.17922916328796
inositol phosphate catabolic process (GO:0071545) 1.17706842932666
N-glycan processing (GO:0006491) 1.1766422611118
peptidyl-threonine dephosphorylation (GO:0035970) 1.17568476940107
microtubule cytoskeleton organization involved in mitosis (GO:1902850) 1.17301392200669
cellular anion homeostasis (GO:0030002) 1.17297263247996
maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) 1.17159642934104
3'-phosphoadenosine 5'-phosphosulfate metabolic process (GO:0050427) 1.17143688549834